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Showing 18 of 441 guides

Infections

What Are Anelloviruses? TTV, Chronic Disease, ME/CFS, And Long COVID

Anelloviruses are persistent viruses that almost all of us carry, and changes in their abundance may reveal an immune system under pressure more reliably than they reveal a virus causing disease.

21 min read
Sexual

Sub-Zero: Icing Your Testicles For Increased Male Performance

It's my birthday, so I think I'll talk about a crazy, unorthodox biohack that I've been doing.

3 min read
Hormonal

Dr. Felice Gersh - PCOS, Menopause, and Estrogen Receptors

In this podcast, we will be discussing how estrogen plays a role in the body.

1 min read
Supplements
Supplements

Yohimbine and Yohimbe: Benefits, Mechanisms, And What The Research Says

Yohimbine is the active alkaloid from Pausinystalia yohimbe bark and a well-studied alpha-2 adrenergic receptor antagonist. This post covers its fat loss and sexual function evidence, mechanisms,…

7 min read
Mitochondria

Mitochondrial Dynamics: DRP1, MFN1, MFN2, And OPA1

Mitochondrial dynamics is the quality-control system that decides when mitochondria fuse, divide, reshape their inner membranes, and send damaged material for removal. R

12 min read
Long COVID

Spike Protein Persistence And The Glycocalyx

Spike protein binds the sugary glycocalyx coating of your blood vessels before it ever reaches ACE2, and the act of binding both tears that protective layer and primes the virus for entry. This post…

13 min read
Supplements

Review of "Reliable" Sources (Updated to 2020)

Gathered Reviews of Suppliers and SourcesDisclaimer: Most of this data is sourced from personal experience, Facebook, or Reddit forums. Be wise and don't buy from some "rando".

24 min read
Brain

Arsenic Lowers IQ and Disrupts the Gut-Brain Axis

Arsenic is so common, but it is not talked about much. It is hidden in our food and supplements, but has devastating effects on the body that we will discuss below.We will also discuss what you can…

9 min read
Supplements

Apigenin: Benefits, CD38/NAD+, Sleep, And The Chamomile Connection

Apigenin is the chamomile flavone that calms the brain at the GABA-A receptor and raises NAD+ by inhibiting CD38, with strong mechanisms in a dish but a serious oral bioavailability problem of…

10 min read
Lab tests

Small Fiber Neuropathy: Causes Beyond Diabetes, and How to Find the Root

Small fiber neuropathy is damage to the tiniest sensory and autonomic nerves, and diabetes is only one of dozens of causes. This is a root-cause guide to what drives it beyond diabetes, how the…

17 min read
Thyroid

Dr. Denis Wilson - Wilson Temperature Syndrome and Regulating Thyroid Function Without Blood Tests

Dr. Denis Wilson and I discuss how to monitor and regulate thyroid function without the need for blood tests.

2 min read
Drugs

Understanding Proton Pump Inhibitors (Part 2)

Last week, I posted about a type of common drug called NSAIDs and their dangerous side effects. This week, we’re going to look at another popular category of drugs: Proton Pump Inhibitors or…

5 min read
Skin

Eczema Beyond The Barrier: The Neuroimmune And Neurovascular Drivers Of Atopic Dermatitis

Eczema is not just a broken barrier or an overactive immune system, it is a feedforward loop where cytokines signal directly to skin nerves and the itch-scratch cycle becomes self-sustaining. Here is…

29 min read
Mindset

Trauma Bonding vs. Stress Bonding: The Biology Of Bonding To The Person Hurting You

Trauma bonding is a strong attachment to a person who alternates harm with affection, and it runs on the same intermittent reward circuitry as addiction. This post covers what actually drives the…

20 min read
Mindset

Why I Don't Drink Alcohol (The Social, Moral and Health Benefits of Not Drinking)

Ever since I gave up alcohol, I very rarely get sick, my sleep has improved drastically, my mental health is much more stable, I have MUCH more confidence in myself, I am more accepting of others, my…

10 min read
Alzheimer's

The 13+ Benefits Of Chitosan And Chitooligosaccharides

In this post, we will discuss the benefits of chitosan and chitosan derivatives.

10 min read
Oxidative stress

Ferroptosis: Iron, Lipid Peroxidation, Glutathione, And Cell Death

Ferroptosis is an iron-dependent form of regulated cell death in which lipid peroxidation overwhelms the cell's membrane-protection systems. R

17 min read
Brain

Reverse Hemorrhage Stroke Degeneration Naturally

A hemorrhagic stroke happens when an artery in the brain leaks or bursts (ruptures) with bleeding directly into the brain (intracerebral) or into the space between the brain's membranes within the…

7 min read