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Showing 18 of 441 guides

Vascular

ApoB And Lp(a): The Cardiovascular Markers That Matter More Than LDL Cholesterol

ApoB and lipoprotein(a) predict heart attacks better than a standard LDL cholesterol number, and most people never test either one. Here is what they are, why they beat LDL-C, how they damage…

13 min read
Infections

191+ Ways To Combat Herpes (Inhibit HSV1 and HSV2)

Herpes is one of the most common sexually transmitted diseases which can affect multiple organ systems including the lips and genitals.In this post, we will discuss herpes (HSV-1 and HSV-2), how it…

17 min read
Mitochondria

Mitochondrial Dynamics: DRP1, MFN1, MFN2, And OPA1

Mitochondrial dynamics is the quality-control system that decides when mitochondria fuse, divide, reshape their inner membranes, and send damaged material for removal. R

12 min read
Mindset

Interview with Tomás J Ryan - Debunking Amnesia

What is learning and memory? Is amnesia really a loss of stored memories or something more? Find out below.

6 min read
Brain

Craniocervical Instability: Causes, Symptoms, Mechanisms, Testing, and How To Improve It

Craniocervical Instability (CCI) is a structural condition in which the ligaments connecting the skull to the upper cervical spine lose their ability to hold the junction stable, allowing excessive…

21 min read
Supplements

The 7+ Benefits Of Blessed Thistle (Cnicus benedictus)

In this post, we will discus the bioactive components of Blessed Thistle, its benefits, my experience, and possible downsides.

3 min read
Supplements

Urolithin A: Mitophagy, Muscle, And The Mitopure Question

Urolithin A is a gut bacterial metabolite that switches on mitophagy, but only about 40% of people make meaningful amounts on their own. Here is the human evidence, the dosing, and the producer…

8 min read
Supplements

Parvalbumin: Why You Can't Supplement For Fish

In this post, we will discuss what parvalbumin is, how it plays a role in chronic illnesses, and what you can do to increase it.

10 min read
Probiotics

Why use uBiome?

uBiome compares your bacteria's DNA to others using OpenBiome, a non-profit. They are using this information for the betterment of mankind by working with clinicians to make fecal microbiota…

2 min read
Alzheimer's

The 8+ Benefits Of J147: A Potent Curcumin Derivative (And How To Make T-006)

Unlike the current drugs approved for Alzheimer's Disease, J147 is neither an acetylcholinesterase inhibitor nor a phosphodiesterase inhibitor, yet it enhances cognition with a short-term…

8 min read
Probiotics

Fecal Microbiota Transplantation: What It Is, How It Works, And What The Evidence Actually Shows

Fecal microbiota transplantation (FMT) is the transfer of processed stool from a healthy donor to restore a depleted microbiome. This post covers the bile acid germination axis, SCFA restoration,…

24 min read
Nootropics

2 Powerful Ways to Use Your Hair As A Nootropic

Have you seen my hairstyle recently? Why would I like to look like a hobo?

2 min read
Mindset

What Is Biohacking?

In this post, we will discuss what is biohacking (and what isn't biohacking), as well as 10 (of the many) biohacks I like to use.

3 min read
Alzheimer's

The 13+ Benefits Of Chitosan And Chitooligosaccharides

In this post, we will discuss the benefits of chitosan and chitosan derivatives.

10 min read
Hormonal

Estrogen Receptors, Estrogenics, And The Rise of Western Disease (Part 1)

In this post we are going to be discussing estrogen receptors and how estrogen affects the body.

20 min read
Alzheimer's

Are You ApoE4? 88+ Ways To Increase Apolipoprotein E (ApoE)

ApoE is a master regulator for many genes implicated in cholesterol metabolism (such as Alzheimer's Disease and Atherosclerosis).In this post, we will discuss the benefits and downsides of ApoE, how…

11 min read
Detox

How Cadmium Damages Mitochondria And What To Do About It

In western society, cadmium (Cd) is found in our everyday environment.It causes toxic effects to the whole body, including the cells and mitochondria.In this post, we will discuss how cadmium affects…

9 min read
Long COVID

Spike Protein Persistence And The Glycocalyx

Spike protein binds the sugary glycocalyx coating of your blood vessels before it ever reaches ACE2, and the act of binding both tears that protective layer and primes the virus for entry. This post…

13 min read