The Origin

Why MyBioHack Exists

Before it was a research library, it was one person trying to work out what was wrong with him. That decade is where every topic on this site came from.

Jacob Gordon receiving cupping therapy

The Beginning

It Started With a Body That Was Failing

Over a decade ago, I found myself struggling with a collection of debilitating health issues that no doctor could explain.

I became a nomad, traveling around the world, watching top doctors from the Mayo Clinic and Ivy League hospitals scratch their heads at my case, then hand me a script for benzodiazepines and antidepressants. Modern medicine had failed me.

“I was so sick of my life and knew there was more to myself. I decided to take a new approach.”

What I Was Dealing With

28 symptoms. Zero answers from conventional medicine.

ADHD and focus issuesAppendix, hernia, UC-type, diverticulitis-like painBiliary/liver/gallbladder/pancreas inflammationBlood pressure issuesBody temperature dysregulationBrain fogCFS and Fibromyalgia painChemical SensitivitiesChronic Infections & mold sensitivitiesCircadian rhythm & sleep issues / insomniaCOPD and lung issuesDetoxification issuesDural holes, headaches from spinal taps (PDPH/POTS)Environmental intolerance (mold, VOCs, haptens)Food SensitivitiesGut dysbiosis, IBS, malabsorption, SIBOHair lossHearing loss and tinnitusLibido issuesLyme/BorreliaMast cells and histamine issuesmTBI and concussions (multiple)Muscle spasms and twitchesRenal pain and nocturiaSensory processing issuesWounds wouldn't healViral outbreaks (chronic)Vision loss in right eye

Every item on this list eventually became a research topic.

What Had to Be Done

Becoming My Own Researcher

My case didn't fit any boxes. So I did what any stubborn, chronically ill person would do. I became my own researcher. I read thousands of studies. I tracked everything. I ran my own experiments.

What I found was that my symptoms weren't random. They were interconnected signals from a system under siege. And once I understood the system, I could start fixing it.

Through n=1 self-experimentation and deep scientific research, I identified the contributing pathways that were driving my illness.

What I Found

Hapten sensitization

Reactive chemical molecules triggering immune responses

Redox/detox impairment due to epigenetic issues

Loss of BH4 via reactive oxygen species (ROS), impairing neurotransmitter production and detox

SALI (CIRS derivative)

Systemic and long-term inflammation stemming from biotoxin exposure and immune dysregulation

Thalamic, Hypothalamic, Basal Ganglia & PFC grey matter inflammation

Neuroinflammation affecting autonomic regulation, cognition, and mood

TLR activation and endotoxemia

Parasites, mold, LPS from gut dysbiosis leading to intestinal and blood-brain barrier permeability

Jacob Gordon outdoors in the Black Hills

What It Turned Into

The research notes became the library

431 articles, 47 chapters, and 43,000+ studies referenced. The story is the reason the library exists. The library is the part that helps you.

Browse the ResearchAbout MyBioHack

Sound familiar?

If you're dealing with complex, overlapping symptoms, you're not alone.

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